Comparison of intrathecal clonidine and dexmedetomidine added with bupivacaine for post-operative analgesia in gynaecological surgeries.

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2023/03/051196
• Lead Sponsor: DR. YOGITA SORTE

Brief Summary

VARIOUS CLINICAL STUDY HAVE FOUND THAT ADMINISTRATION OF INTRATHECAL CLONIDINE AND DEXMEDETOMIDINE ADDED WITH BUPIVACAINE PROLONGS THE DURATION OF SENSORY AND MOTOR BLOCKADE AS WELL AS DURATION OF ANALGESIA. HOWEVER THESE ARE LIMITED DATA AVAILABLE ON COMPARING INTRATHECAL CLONIDINE AND DEXMEDETOMIDINE ADDED WITH BUPIVACAINE.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-01-04
• Last Update Posted: 2023-03-30

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Female
• Target Recruitment: 100

Inclusion Criteria

• 1.Informed written consent for participation in study.
• 2.Patients posted for gynaecological surgeries.
• 3.ASA physical status I and II.

Exclusion Criteria

• Contraindication to subarachnoid block.
• Allergy to local anaesthetic or study drug.
• Uncontrolled or labile hypertension.
• Patients taking any analgesics, sedative or antihypertensive drugs.
• Neurological disorders.
• Psychiatric disorders.
• Uncooperative patients.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
TO STUDY AND COMPARE THE ONSET OF ANALGESIA, DURATION OF MOTOR BLOCKADE, DURATION OF SENSORY BLOCKADE, HAEMODYNAMIC PARAMETERS OF INTRATHECAL CLONIDINE AND DEXMEDETOMIDINE ADDED WITH BUPIVACAINE.	TO STUDY AND COMPARE THE ONSET OF ANALGESIA, DURATION OF MOTOR BLOCKADE, DURATION OF SENSORY BLOCKADE, HAEMODYNAMIC PARAMETERS OF INTRATHECAL CLONIDINE AND DEXMEDETOMIDINE ADDED WITH BUPIVACAINE.

Secondary Outcome Measures

Name	Time	Method
TO STUDY AND COMPARE THE ONSET OF ANALGESIA, DURATION OF MOTOR BLOCKADE, DURATION OF SENSORY BLOCKADE, HAEMODYNAMIC PARAMETERS OF INTRATHECAL CLONIDINE AND DEXMEDETOMIDINE ADDED WITH BUPIVACAINE.	TO STUDY AND COMPARE THE ONSET OF ANALGESIA, DURATION OF MOTOR BLOCKADE, DURATION OF SENSORY BLOCKADE, HAEMODYNAMIC PARAMETERS OF INTRATHECAL CLONIDINE AND DEXMEDETOMIDINE ADDED WITH BUPIVACAINE.

Trial Locations

Locations (1)

PEOLPES COLLEGE OF MEDICAL SCIENCES AND RESEARCH CENTRE; 🇮🇳 Bhopal, MADHYA PRADESH, India

PEOLPES COLLEGE OF MEDICAL SCIENCES AND RESEARCH CENTRE

🇮🇳Bhopal, MADHYA PRADESH, India

DR YOGITA SORTE

Principal investigator

9806179234

yogitanimje84@gmail.com