A comparative clinical study of intrathecal clonidine and dexmedetomidine added with bupivacaine for post-operative analgesia in gynaecological surgeries.

DR. YOGITA SORTE1 个研究点分布在 1 个国家目标入组 100 人开始时间: 2023年1月4日最近更新: 2023年3月30日

试验速览

阶段: 不适用
状态: 尚未招募
发起方
入组人数: 100
试验地点: 1
主要终点: TO STUDY AND COMPARE THE ONSET OF ANALGESIA, DURATION OF MOTOR BLOCKADE, DURATION OF SENSORY BLOCKADE, HAEMODYNAMIC PARAMETERS OF INTRATHECAL CLONIDINE AND DEXMEDETOMIDINE ADDED WITH BUPIVACAINE.

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

VARIOUS CLINICAL STUDY HAVE FOUND THAT ADMINISTRATION OF INTRATHECAL CLONIDINE AND DEXMEDETOMIDINE ADDED WITH BUPIVACAINE PROLONGS THE DURATION OF SENSORY AND MOTOR BLOCKADE AS WELL AS DURATION OF ANALGESIA. HOWEVER THESE ARE LIMITED DATA AVAILABLE ON COMPARING INTRATHECAL CLONIDINE AND DEXMEDETOMIDINE ADDED WITH BUPIVACAINE.

研究设计

研究类型: Interventional
分配方式: Other
盲法: Participant Blinded

入排标准

年龄范围: 18.00 Year(s) 至 50.00 Year(s)（—）
性别: Female

入选标准

•1.Informed written consent for participation in study.
•2.Patients posted for gynaecological surgeries.
•3.ASA physical status I and II.

排除标准

•Contraindication to subarachnoid block.
•Allergy to local anaesthetic or study drug.
•Uncontrolled or labile hypertension.
•Patients taking any analgesics, sedative or antihypertensive drugs.
•Neurological disorders.
•Psychiatric disorders.
•Uncooperative patients.

结局指标

主要结局

TO STUDY AND COMPARE THE ONSET OF ANALGESIA, DURATION OF MOTOR BLOCKADE, DURATION OF SENSORY BLOCKADE, HAEMODYNAMIC PARAMETERS OF INTRATHECAL CLONIDINE AND DEXMEDETOMIDINE ADDED WITH BUPIVACAINE.

时间窗: TO STUDY AND COMPARE THE ONSET OF ANALGESIA, DURATION OF MOTOR BLOCKADE, DURATION OF SENSORY BLOCKADE, HAEMODYNAMIC PARAMETERS OF INTRATHECAL CLONIDINE AND DEXMEDETOMIDINE ADDED WITH BUPIVACAINE.

次要结局

TO STUDY AND COMPARE THE ONSET OF ANALGESIA, DURATION OF MOTOR BLOCKADE, DURATION OF SENSORY BLOCKADE, HAEMODYNAMIC PARAMETERS OF INTRATHECAL CLONIDINE AND DEXMEDETOMIDINE ADDED WITH BUPIVACAINE.(TO STUDY AND COMPARE THE ONSET OF ANALGESIA, DURATION OF MOTOR BLOCKADE, DURATION OF SENSORY BLOCKADE, HAEMODYNAMIC PARAMETERS OF INTRATHECAL CLONIDINE AND DEXMEDETOMIDINE ADDED WITH BUPIVACAINE.)

研究者

发起方

DR. YOGITA SORTE

申办方类型

Other [self]

研究点 (1)

Loading locations...

相似试验

已完成

不适用

Comparison of clonidine and dexmedtomidine as additives to the routinely used drug for spinal anaesthesia: bupivacaine in pregnant females delivering by the surgical method, commonly known as Caesarean delivery.

CTRI/2020/10/028490Department of Anaesthesiology90

已完成

4 期

A Clinical trial To compare the effect of dexmedetomidine and clonidine during laproscopic uterus removal operation under general anaesthesia.

CTRI/2018/12/016609SHANMUGAVALLI E100

尚未招募

不适用

comparison between 2 drugs in gynecological surgery

CTRI/2023/10/059020DR SOMSUNDAR R G90

尚未招募

不适用

A study to understand the advantages of intrathecal clonidine compared to combination of clonidine with fentanyl in patients undergoing laparoscopic surgeries

CTRI/2019/08/020928Bangalore Medical College and Research Institute60

尚未招募

不适用

Comparison of inj. Dexmedetomedine and magnesium sulphate in spinal Anaesthesia to prevent Shivering in LSCS.

CTRI/2023/02/049601Department of Anaesthesiology150