MedPath

ate neonatal neurological outcome in infants with prenatally diagnosed duct dependent CHD and its relation with fetal and neonatal cerebral perfusio

Completed
Conditions
congenital heart defect
heart disease
10010394
10028920
Registration Number
NL-OMON40142
Lead Sponsor
niversitair Medisch Centrum Groningen
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
25
Inclusion Criteria

Mothers of fetusses suspected of CHD and their subsequent newborn infant with duct dependent congenital heart defect
Gestational age > 35 weeks

Exclusion Criteria

Large congenital cerebral malformation
Severe chromosomal defect

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>Qualitative assessment of GMs according to Prechtl*s method. In addition, we<br /><br>will obtain motor optimality scores for more detailed analysis of the GMs;</p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Near-infrared Spectroscopy: cerebral (rcSO2) and systemic (rrSO2) oxygen<br /><br>saturation and FTOE;<br /><br>Pulsatility index (PI) and if possible maximum velocity of various arterial<br /><br>vessels, measured with Doppler ultrasound.</p><br>
© Copyright 2025. All Rights Reserved by MedPath