Early outcome of prenatally diagnosed Ventriculomegaly by general movement Assessment

Not Applicable

• Conditions: Ventriculomegaly; Neonatal Diseases

• Registration Number: ISRCTN17606645
• Lead Sponsor: niversity Medical Center Groningen (Netherlands)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-11-12
• Last Update Posted: 10 December 2019
• Study Completion: 2019-12-31

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

1. Newborn child
2. Aged less than one week
3. Having been diagnosed with ventriculomegaly (>10 mm ventricular width) as foetus

Exclusion Criteria

1. Diagnosis of spina bifida
2. First ultrasound at more than 23 weeks of gestation

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> To determine whether the short-term neurological outcome of surviving children diagnosed with prenatally diagnosed ventriculomegaly is associated with the extent of VM before birth.<br><br> The quality of fidgety general movements (FMs) and the motor optimality score (MOS) will be determined at 3 months (11-15 weeks) after term, from video recordings.<br>

Secondary Outcome Measures

Name	Time	Method
<br> To determine whether the etiology of VM and presence of associated anomalies is associated with short-term neurological outcome of children with prenatally diagnosed VM.<br><br> As secondary outcome measure the quality of GMs and the MOS will be assessed at 1 week after birth, and in preterm children (born before 36 weeks) also at term equivalent age (40 weeks ± 14 days post menstrual age), and in all children around 18 weeks (16-20 weeks) after term.<br>