Prospective Investigation of the Influence of Triglyceride Tolerance on Cardiovascular Outcomes in Patients With Coronary Artery Disease

Universität des Saarlandes1 site in 1 country514 target enrollmentFebruary 1, 2008

ConditionsCoronary Artery Disease Diabetes Metabolic Syndrome Glucose Tolerance Hyperlipidemia

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Coronary Artery Disease
Sponsor: Universität des Saarlandes
Enrollment: 514
Locations: 1
Primary Endpoint: Parameters of triglyceride tolerance and glucose tolerance in correlation to cardiovascular events, cardiovascular mortality, total mortality.
Status: Completed
Last Updated: 5 months ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to prospectivly analyze the correlation of triglyceride tolerance and glucose tolerance with cardiovascular morbidity and mortality in patients with stable coronary artery disease within 18 months and to determine, whether measurement of triglyceride tolerance can discriminate patients at risk for cardiovascular events.

Registry

clinicaltrials.gov

Start Date

February 1, 2008

End Date

August 1, 2013

Last Updated

5 months ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Universität des Saarlandes

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Stable CAD

Exclusion Criteria

•Acute Coronary Syndrom
•Relevant Arrhythmias
•Severe valvular heart disease
•Decompensated heart failure
•Severe inflammtory disease (infectious, rheumatoid)
•Metabolic diseases (e.g. thyroid)
•Inability to swallow
•Liver or kidney failure
•Lactose intolerance
•Fat intolerance (e.g. chronic pancreatitis, gall stones)

Outcomes

Primary Outcomes

Parameters of triglyceride tolerance and glucose tolerance in correlation to cardiovascular events, cardiovascular mortality, total mortality.

Time Frame: 48 months after inclusion.

Secondary Outcomes

Waist-to-Hip ratio, nutrition protocol, physical activity, non-invasive endothelial function, body fat composition, other biomarkers of lipid and glucose metabolism.(Directly after inclusion.)