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临床试验/NCT00628524
NCT00628524已完成不适用

Prospective Investigation of the Influence of Triglyceride Tolerance on Cardiovascular Outcomes in Patients With Coronary Artery Disease

Universität des Saarlandes1 个研究点 分布在 1 个国家目标入组 514 人开始时间: 2008年2月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
514
试验地点
1
主要终点
Parameters of triglyceride tolerance and glucose tolerance in correlation to cardiovascular events, cardiovascular mortality, total mortality.

研究概览

简要总结

The purpose of this study is to prospectivly analyze the correlation of triglyceride tolerance and glucose tolerance with cardiovascular morbidity and mortality in patients with stable coronary artery disease within 18 months and to determine, whether measurement of triglyceride tolerance can discriminate patients at risk for cardiovascular events.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Stable CAD

排除标准

  • Acute Coronary Syndrom
  • Relevant Arrhythmias
  • Severe valvular heart disease
  • Decompensated heart failure
  • Severe inflammtory disease (infectious, rheumatoid)
  • Metabolic diseases (e.g. thyroid)
  • Inability to swallow
  • Liver or kidney failure
  • Lactose intolerance
  • Fat intolerance (e.g. chronic pancreatitis, gall stones)
  • Malignant Disease
  • Psychiatric Diseases (including alcohol / drug abuse)
  • Pregnancy

结局指标

主要结局

Parameters of triglyceride tolerance and glucose tolerance in correlation to cardiovascular events, cardiovascular mortality, total mortality.

时间窗: 48 months after inclusion.

次要结局

  • Waist-to-Hip ratio, nutrition protocol, physical activity, non-invasive endothelial function, body fat composition, other biomarkers of lipid and glucose metabolism.(Directly after inclusion.)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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