Effect of Medium Chain Triglyceride Consumption on Appetite
Not Applicable
Completed
- Conditions
- Obesity
- Interventions
- Dietary Supplement: Test breakfast
- Registration Number
- NCT01952977
- Lead Sponsor
- St. Luke's-Roosevelt Hospital Center
- Brief Summary
The purpose of this study is to test the effects of medium chain triglyceride consumption, relative to long chain triglycerides, on hormones involved in appetite regulation and food intake in overweight men. We expect medium chain triglycerides to reduce appetite and food intake and to do so by increasing levels of hormones known to be involved in satiety and reduce levels of those involved in appetite.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 17
Inclusion Criteria
- Males
- Weight stable (<10 lb over previous 3 months)
- Overweight (body mass index 25-29.9)
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Exclusion Criteria
- Smokers
- Excessive caffeine users
- Severe health conditions
- Allergy to food products/ingredients in the study
- Taking medications known to affect energy expenditure or gastrointestinal function
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description MCT Test breakfast MCT oil (20 g) was included in the test breakfast LCT Test breakfast Corn oil (20 g) was included in the test breakfast
- Primary Outcome Measures
Name Time Method Food intake up to 3 hours Intake at an ad libitum meal 3 h after test oil consumption (Study 1) or 1 h after a pre-load containing the test oil (Study 2)
- Secondary Outcome Measures
Name Time Method Peptide YY 3 hours Glucagon-like peptide 1 3 hours Insulin 3 hours Triglycerides 3 hours Leptin 3 hours Ghrelin 3 hours
Trial Locations
- Locations (1)
New York Obesity Nutrition Research Center
🇺🇸New York, New York, United States