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临床试验/EUCTR2005-002580-85-DK
EUCTR2005-002580-85-DK进行中(未招募)1 期

Acute haemodynanic effects of Treatment with ACE inhibitores in patients with severe Aortic Stenosis

Rigshospitalet0 个研究点目标入组 64 人开始时间: 2005年7月11日最近更新:
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试验速览

阶段
1 期
状态
进行中(未招募)
入组人数
64

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional clinical trial of medicinal product

入排标准

性别
All

入选标准

  • Valvular aortic stenosis with a aortic valve area <1,0 cm2
  • Age > 18 years
  • Willingness to give written informed consent
  • For patients with symptomatic aortic stenosis at least one of following
  • Stable angina pectoris
  • Syncope at exertion
  • Dizziness at exertion
  • Previous pulmonary oedema
  • Patients in New York Heart Association functional class II-IV
  • Are the trial subjects under 18? no
  • Number of subjects for this age range:
  • F.1.2 Adults (18-64 years) yes
  • F.1.2.1 Number of subjects for this age range
  • F.1.3 Elderly (>=65 years) yes
  • F.1.3.1 Number of subjects for this age range

排除标准

  • Sitting systolic pressure < 100 mmHg
  • Creatinine > 200 mM at screening
  • Renal artery stenosis
  • Pregnancy or planned pregnancy
  • Participation in other studies
  • Any patient characteristic that may interfere with compliance to the study protocol
  • Treated with ACE-inhibitor or angiotensin receptor blocker within the last month
  • Known allergy to ACE-inhibitors

研究者

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