EUCTR2005-002580-85-DK进行中(未招募)1 期
Acute haemodynanic effects of Treatment with ACE inhibitores in patients with severe Aortic Stenosis
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中(未招募)
- 入组人数
- 64
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Valvular aortic stenosis with a aortic valve area <1,0 cm2
- •Age > 18 years
- •Willingness to give written informed consent
- •For patients with symptomatic aortic stenosis at least one of following
- •Stable angina pectoris
- •Syncope at exertion
- •Dizziness at exertion
- •Previous pulmonary oedema
- •Patients in New York Heart Association functional class II-IV
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •Sitting systolic pressure < 100 mmHg
- •Creatinine > 200 mM at screening
- •Renal artery stenosis
- •Pregnancy or planned pregnancy
- •Participation in other studies
- •Any patient characteristic that may interfere with compliance to the study protocol
- •Treated with ACE-inhibitor or angiotensin receptor blocker within the last month
- •Known allergy to ACE-inhibitors
研究者
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