Evaluation of Hospitalization for Anorexia Nervosa (EVALuation de l'Apport de l'HOSPITalisation Pour Anorexie Mentale : EVALHOSPITAM)

• Conditions: Anorexia Nervosa
• Interventions: Other: inpatient treatment

• Registration Number: NCT00910169
• Lead Sponsor: Institut Mutualiste Montsouris

Brief Summary

The objective of this research is to evaluate the efficacy of five different in-patient treatment modalities and predictive factors of outcome for anorexia nervosa. The primary hypothesis is that the different treatment types impact outcome of patients at discharge from inpatient treatment and at one year follow-up, even after adjustment for confounding factors (age, length of illness, number of previous hospitalizations, clinical state at intake).

Detailed Description

This study will evaluate global, psychiatric, somatic and psychosocial outcome for inpatients with anorexia nervosa through three evaluations (intake, discharge and one-year follow-up). The study will also consider five types of in-patient treatment in a naturalistic setting (i.e., patients will not be assigned to different treatment conditions; rather, we will study inpatient care as it exists today). The five treatment modalities to be studied are:

1. Discharge weight objectives.

2. The practice of a separation period.

3. The use of clear nutritional and dietary objectives (cognitive/behavioural).

4. The intensity of family involvement in treatment.

5. Stabilisation phase before ending inpatient treatment.

Study Timeline

• Study Start: 2009-03
• Status Verified: 2009-05
• Study First Submitted: 2009-05-26
• Study First Submitted QC: 2009-05-28
• Study First Posted: 2009-05-29
• Last Update Submitted: 2012-08-06
• Last Update Posted: 2012-08-07
• Primary Completion: 2012-10
• Study Completion: 2012-10

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

• All patients who accept participation between 8 and 50 years old, consecutively hospitalized for a DSM IV diagnosis of Anorexia Nervosa in one of the departments participating in this research by necessity of physical condition (BMI < 15, rapid weight loss) or psychological condition
• Parents of participating patients still living with their parents who accept participation

Exclusion Criteria

• Refusal of research
• Patients who do not speak French
• Patients with a related somatic illness (diabetes, Crohn's disease, metabolic illness)
• Patients not covered by social security health insurance

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
inpatient treatment	inpatient treatment	naturalistic treatment no modification: observational study

Primary Outcome Measures

Name	Time	Method
Morgan and Russell score	one year follow-up

Secondary Outcome Measures

Name	Time	Method
Nutritional status	one year follow-up
Psychiatric symptoms and disorders	one year follow-up
Somatic symptoms and complications	one year follow-up
Social adjustment	one year follow-up
Re-hospitalization	one year follow-up
Cognitive functioning	one year follow-up
Family relationships	one year follow-up
Eating disorders symptoms and diagnosis	one year follow-up
Quality of life	one year follow-up

Trial Locations

Locations (1)

Insitut Mutualiste Montsouris; 🇫🇷 Paris, France