A multicenter randomized controlled trial for Wen-Jing Hua-Yu Tong-Luo Decoction in relieving chemotherapy induced peripheral neuropathy (CIPN)
- Conditions
- chemotherapy induced peripheral neuropathy(CIPN)
- Registration Number
- ITMCTR1900002693
- Lead Sponsor
- onghua Hospital Affiliated to Shanghai University of traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
(1) patients with numbness of hands and feet after chemotherapy were diagnosed as peripheral neuropathy;
(2) chemotherapy patients with definite diagnosis of cytology or pathology;
(3) patients aged 18 to 80 years;
(4) KPS (Karnofsky's speech status) score is more than 50;
(5) estimated survival time >=6 months;
(6) normal blood picture, renal function, liver function and various biochemical indexes;
(7) the patient has good compliance, understands and agrees to accept the treatment, and signs the informed consent.
1. patients with original nervous system diseases;
2. diabetic patients who may cause peripheral sensory abnormality;
3. patients undergoing other drugs or radiotherapy that may cause peripheral neurotoxicity;
4. mental patients with cognitive loss or mental disorder;
5. patients with severe primary diseases of cardiovascular, cerebrovascular, liver, kidney and hematopoietic system;
6. women who are breastfeeding, pregnant or preparing for pregnancy;
7. people with allergic constitution and multiple drug allergy.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Grading of peripheral neuropathy;
- Secondary Outcome Measures
Name Time Method