Viral and Host Factors in the Transmission and Pathogenesis of HIV
- Conditions
- HIV Infections
- Registration Number
- NCT00219947
- Lead Sponsor
- Rockefeller University
- Brief Summary
To study the collection of blood from individuals known to be at high risk for HIV-infection or who have been recently infected with HIV.
The data collected are used for diagnostic, prognostic and management decisions as outlined by current HIV-1 Treatment Guidelines.
- Detailed Description
This phlebotomy protocol permits the collection of blood from individuals known to be at high risk for HIV-infection or who have been recently infected with HIV.
Participants will have from 10 to 60 ml (approximately 1 to 4 tablespoons) of blood drawn for one or all of the following tests:
* T cell subset enumeration
* Serologic reactivity with HIV antigens
* Viral load assays by bDNA, PCR, or RT-PCR
* Routine Laboratory assessments (chemistries, liver function tests, hepatitis serology, RPR)
* HIV-1 Resistance Testing
These data are used for diagnostic, prognostic and management decisions as outlined by current HIV-1 Treatment Guidelines
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 600
recently infected with HIV-1 HIV-1 negative, and at high risk for infection
none
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Participants are tested for HIV-1 RNA levels, the presence of antibodies to HIV antigens, and T cell subsets first visit
- Secondary Outcome Measures
Name Time Method Data will be used for diagnostic, prognostic and management decisions as outlined by current HIV-1 Treatment first visit
Trial Locations
- Locations (2)
Aaron Diamond AIDS Research Center (ADARC)
🇺🇸New York, New York, United States
Rockefeller University Hospital
🇺🇸New York, New York, United States
Aaron Diamond AIDS Research Center (ADARC)🇺🇸New York, New York, United States