Effect of an Low Carbon High Fat Diet on Pain- and Quality of Life in Patients With Lipedema

Not Applicable

Completed

• Conditions: Lipedema; Obesity, Morbid
• Interventions: Dietary Supplement: Low carbohydrate high fat diet

• Registration Number: NCT03710798
• Lead Sponsor: Helse Nord-Trøndelag HF

Brief Summary

Lipedema is a chronic disease with unproportional, symmetrical fat accumulation in the lower extremities. Patients experience pain in affected areas, and reduced quality of life. Today's treatment is physiotherapy and surgery (liposuction). Recent research shows that ketogenic-diet with low carbohydrate, high fat (LCHF) conant can lead to reduced pain, increased quality of life and change in body composition. Goals: Investigate the effect of LCHF diet on pain, quality of life and body composition.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-10-01
• Study First Submitted: 2018-10-16
• Study First Submitted QC: 2018-10-16
• Study First Posted: 2018-10-18
• Primary Completion: 2019-01-10
• Study Completion: 2019-01-10
• Status Verified: 2019-02
• Last Update Submitted: 2019-02-25
• Last Update Posted: 2019-02-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 10

Inclusion Criteria

• weight stable over the last three months (+ 2-3 kg)
• not currently dieting to loose weight.
• willing to meet for weekly follow-ups during the intervention and the reintroduction of a regular diet.
• sign an informed consent before entering the study.

Exclusion Criteria

• pregnant or breast feeding
• history of infectious diseases
• medication known to affect obesity
• enrolment in any other obesity treatment
• have had a bariatric surgery
• history of psychological disorders
• mentally disabled
• not mastering a Scandinavian language
• having a malign disease or any disease that leads to dietary advice that is not consistent with intervention advices in the study

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Low carbohydrate high fat diet	Low carbohydrate high fat diet	Low carbohydrate high fat (LCHF) diet

Primary Outcome Measures

Name	Time	Method
Lymphedema Quality of Life questionnaire	6 weeks
Pain indicated on a visual analog scale	6 weeks

Trial Locations

Locations (1)

Obesity Clinic, St Olavs Hospital; 🇳🇴 Trondheim, Norway