The Effects of AZT and Ibuprofen on HIV-Infected Patients With Hemophilia
Not Applicable
Completed
- Conditions
- HIV InfectionsHemophilia A
- Registration Number
- NCT00002276
- Lead Sponsor
- University of Pittsburgh
- Brief Summary
To determine if platelet dysfunction and/or pharmacologic drug interaction occurs in patients taking both AZT and ibuprofen, which might account for enhanced bleeding tendency.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie AZT and ibuprofen interactions in HIV-infected hemophiliacs?
How does AZT affect platelet function in patients with Hemophilia A and HIV co-infection?
Are there specific biomarkers that predict enhanced bleeding risk when combining AZT and ibuprofen in HIV patients?
What adverse events are associated with concurrent AZT and ibuprofen use in HIV-positive individuals with hemophilia?
How does the pharmacokinetic profile of AZT and ibuprofen compare to standard-of-care antiretroviral and anti-inflammatory therapies in HIV-infected hemophiliacs?
Trial Locations
- Locations (1)
Hemophilia Ctr of Western PA / Univ of Pittsburgh
🇺🇸Pittsburgh, Pennsylvania, United States
Hemophilia Ctr of Western PA / Univ of Pittsburgh🇺🇸Pittsburgh, Pennsylvania, United States