A study of patient with small peripheral resectable non-small cell lung cancer (<2cm) to determine whether sublobar resection results in the same disease-free survival as lobectomy

The National Cancer Institute0 个研究点目标入组 15 人开始时间: 2010年3月17日最近更新: 2022年8月9日

适应症

试验速览

暂无简介。

•Suspected or proven non-small cell lung cancer (NSCLC), meeting both preoperative and intraoperative criteria:
•Preoperative criteria - Peripheral lung nodule = 2 cm by computed tomography (CT scan) AND Center of the tumor must be located in the outer third of the lung in either the transverse, coronal, or sagittal plan AND Tumor location must be suitable for either lobar or sublobar resection (wedge resection or segmentectomy) AND No pure ground opacities or pathologically confirmed N1 or N2 disease
•Intraoperative criteria - Histologically confirmed NSCLC AND Confirmation of N0 status by frozen section examination of nodal levels 4, 7, and 10 on the right side and 5, 6, 7, and 10 on the left side (Levels 4 and 7 nodes may be sampled up to 6 weeks preoperatively by mediastinoscopy, endobronchial ultrasound (EBUS), and/or endoscopic ultrasound (EUS), or at the time of thoracotomy or video-assisted thoracoscopic surgery (VATS) exploration)

•Evidence of locally advanced or metastatic disease
•Prior chemotherapy or radiotherapy for this malignancy
•Eastern Cooperative Oncology Group (ECOG) Performance status > 2
•Any other malignancy within the past 3 years except for non-melanoma skin cancer, superficial bladder cancer, or carcinoma in situ of the cervix

发起方

The National Cancer Institute