ACTRN12610000139077尚未招募未知
A trial of patients with a lower limb arterial tournique and whether an increase in inspired oxygen concentration at the time of reperfusion has any effect on platelet activation, as assessed by flow cytometry and thromboelastography
适应症
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 入组人数
- 45
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 80 Years（—）
- 性别
- All
入选标准
- •1. Adult patients undergoing lower limb surgery that requires the use of a tourniquet for more than 45 minutes
- •2. American Society of Anaesthesiology (ASA) grade 1 or 2
排除标准
- •1. Patients taking any antiplatelet medication 2. Confirmed coagulation disorder (pathological or drug induced) 3. Platelet count less then 80 x 109/l 4. Blood urea greater than 8.0 mmol/L 5. Systemic infection 6. Confirmed systemic Inflammatory diseases 7. Documented pregnancy 8. Documented malignancy 9. Trauma other than the ipsilateral lower limb 10. Multiple tourniquet episodes 11. Likely intraoperative O2 requirement > 30%
研究者
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