ACTRN12609000183280
Not Yet Recruiting
N/A
A trial of patients with an upper limb arterial tournique and whether an increase in inspired oxygen concentration at the time of reperfusion has any effect on platelet activation, as assessed by flow cytometry and thromboelastography
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Ischaemic reperfusion injuries
- Sponsor
- Royal Perth Hospital
- Enrollment
- 45
- Status
- Not Yet Recruiting
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Adult patients undergoing upper limb surgery that requires the use of a tourniquet for more than 45 minutes
- •2\. American Society of Anaesthesiology (ASA) grade 1 or 2
Exclusion Criteria
- •1\. Patients taking any antiplatelet medication
- •2\. Confirmed coagulation disorder (pathological or drug induced)
- •3\. Platelet count less then 80 x 109/l
- •4\. Blood urea greater than 8\.0 mmol/L
- •5\. Systemic infection
- •6\. Confirmed systemic Inflammatory diseases
- •7\. Documented pregnancy
- •8\. Documented malignancy
- •9\. Trauma other than the ipsilateral upper limb
- •10\. Multiple tourniquet episodes
Outcomes
Primary Outcomes
Not specified
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