Comparison of Different Types of Surgery in Treating Patients With Stage IA Non-Small Cell Lung Cancer

Not Applicable

• Conditions: ung Cancer; Lung Cancer; Cancer - Lung - Non small cell

• Registration Number: ACTRN12610000217000
• Lead Sponsor: The National Cancer Institute

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-03-17
• Study Completion: 2020-11-11
• Last Update Posted: 9 August 2022

Recruitment & Eligibility

• Status: Stopped early
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

Suspected or proven non-small cell lung cancer (NSCLC), meeting both preoperative and intraoperative criteria:
Preoperative criteria - Peripheral lung nodule = 2 cm by computed tomography (CT scan) AND Center of the tumor must be located in the outer third of the lung in either the transverse, coronal, or sagittal plan AND Tumor location must be suitable for either lobar or sublobar resection (wedge resection or segmentectomy) AND No pure ground opacities or pathologically confirmed N1 or N2 disease
Intraoperative criteria - Histologically confirmed NSCLC AND Confirmation of N0 status by frozen section examination of nodal levels 4, 7, and 10 on the right side and 5, 6, 7, and 10 on the left side (Levels 4 and 7 nodes may be sampled up to 6 weeks preoperatively by mediastinoscopy, endobronchial ultrasound (EBUS), and/or endoscopic ultrasound (EUS), or at the time of thoracotomy or video-assisted thoracoscopic surgery (VATS) exploration)

Exclusion Criteria

Evidence of locally advanced or metastatic disease
Prior chemotherapy or radiotherapy for this malignancy
Eastern Cooperative Oncology Group (ECOG) Performance status > 2
Any other malignancy within the past 3 years except for non-melanoma skin cancer, superficial bladder cancer, or carcinoma in situ of the cervix

Study & Design

• Study Type: Interventional
• Study Design: Not specified