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ALSUC in refractory GERD

Phase 3
Recruiting
Conditions
GERD.
Gastro-esophageal reflux disease
Registration Number
IRCT20211203053263N3
Lead Sponsor
Ilam University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
200
Inclusion Criteria

Patients who remained symptomatic (assessed by daily reflux questionnaire) with a standard dose of PPI after a trial period of treatment of at least 2 months.

Exclusion Criteria

non-compliant
inappropriate use of PPI
Other diseases that can mimic the symptoms of GERD include achalasia, eosinophilic esophagitis, infectious esophagitis, pill esophagitis, gastroparesis, and esophageal stricture or cancer and functional dyspepsia according to the Rome4 criteria.

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
GERD symptoms severity and frequency during and 6 weeks after treatment. Timepoint: During intervention and 6 weeks after treatment. Method of measurement: Questionnaire.
Secondary Outcome Measures
NameTimeMethod
Compliance of patient. Timepoint: During intervention. Method of measurement: Questionnaire.
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