NCT01711996撤回不适用
The Correlation Between Renal Injury and Biomarkers in Pediatric Ureteropelvic Junction Obstruction Patients
适应症
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- The level of urinary NGAL and the degree of renal injury
研究概览
简要总结
Urinary Neutrophil gelatinase associated lipocalin (NGAL) has been recently reported to be related with the degree of hydronephrosis in pediatric ureteropelvic junction obstruction (UPJO) patients. We are trying to analyze whether it is related with the grade of renal injury in UPJO patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- — 至 3 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •<Group 1>
- •0-3 year old patients with SFU grade 2 or more hydronephrosis without ureteral dilatation
- •needs pyeloplasty due to differential renal function (DRF)<40%, decreased DRF by more than 5%, development of urinary tract infection, development of urinary stone, and development of pain related with UPJO <Group 2>
- •0-3 year old patients with SFU grade 3 or 4 hydronephrosis without ureteral dilatation
- •doesn't meet the above criteria for the indication of pyeloplasty <Group 3>
- •0-3 year old children without any abnormality of urinary tract
排除标准
- •<Group 1>
- •patients with contralateral disease affecting DRF
- •history of previous urinary tract surgery
- •follow up loss before diuretic renogram performed at 6-12 months from operation <Group 2, 3>
- •patients with contralateral disease affecting DRF
- •history of previous urinary tract surgery
结局指标
主要结局
The level of urinary NGAL and the degree of renal injury
时间窗: 6 month after operation
Analysis of correlation between the level of urinary NGAL and the degree of renal injury
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
已完成
不适用
Assessment of Acute Renal Injury During Partial Nephrectomy Using Neutrophil Gelatinase-associated Lipocalin (NGAL): Prospective Comparative Study Between Open, Video-assisted Minilaparotomy, Laparoscopic, and Robotic-assisted Laparoscopic Surgerythe Patients With Partial NephrectomyNCT01891032Yonsei University160
已完成
不适用
Role of NGAL and Cystatin C in Prediction of Acute Kidney Injury Covid-19 InfectionBiochemical Markers ,NGAL,Cystatin c, Acute Kidneyinjury, Covid 19NCT04603664Ain Shams University100
Unknown
不适用
Neutrophil Gelatinase-associated Lipocalin as a New Biomarker to Detect Acute Kidney Injury in Postoperative Cardiac SurgeryCardiac SurgeryNCT01594788Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau340
已完成
不适用
Serum Neutrophil Gelatinase-associated Lipocalins (NGAL) and Chronic Kidney DiseaseChronic Kidney DiseasesCKDNGALNeutrophil Gelatinase-associated LipocalinEmergency DepartmentAcute Kidney InjuryAKINCT04008810Hillerod Hospital, Denmark1,032
已完成
不适用
Neutrophil Gelatinase-associated Lipocalin Concentration in Coronary Artery DiseaseAtherosclerosisCoronary Artery DiseaseNCT00749281Cardiovascular Research Society, Greece73