Shunt Evaluation With ALPE System in Thoracic Surgery
Completed
- Conditions
- Mechanical VentilationThoracic Diseases
- Registration Number
- NCT02968550
- Lead Sponsor
- Università degli Studi di Ferrara
- Brief Summary
. The aim of this study, thus, is to evaluate shunt fraction and markers of alveolar distress during one lung ventilation (OLV) at different levels of positive end expiratory pressure (PEEP). Moreover, investigators will focus on predicting factors of high shunt levels during OLV.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 41
Inclusion Criteria
- patients scheduled for thoracoscopic lobectomy or thoracoscopic wedge resection in lateral decubitus.
- patients American Society of Anesthesiologists Physical Status Classification score of 1-3
Exclusion Criteria
- Patients with hemodynamic instability,
- Patients with severe chronic respiratory failure
- Patients with preoperative anemia (hemoglobin <10 g 100 ml-1)
- Patients requiring unplanned conversion to thoracotomy
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pulmonary shunt evaluated with ALPE system every 30 minutes after the start of surgery up to 3 evaluations, up to 90 minutes
- Secondary Outcome Measures
Name Time Method predictors of high intraoperative shunt The outcome is assessed 15 minutes after one lung ventilation All patients admitted to the study received a preoperative physiologic assessment with a cardiovascular evaluation and spirometry. After 15 minutes of one lung ventilation, the pulmonary shunt is evaluated. Therefore, all clinical variable evaluated during preoperative assessment will be compared with the pulmonary shunt
Trial Locations
- Locations (1)
Azienda Ospedaliero Universitaria Sant'Anna
🇮🇹Ferrara, Italy