Mat Pilates and Vascular Function in Obese Females

Not Applicable

Completed

• Conditions: Elevated Blood Pressure; Obese
• Interventions: Behavioral: Mat Pilates training

• Registration Number: NCT03907384
• Lead Sponsor: Marymount University

Brief Summary

Obesity is associated with progressive decreases in arterial health and function. It is crucial to prevent or reduce the negative effects of aging on the vasculature by implementing appropriate lifestyle interventions, such as exercise training. We examined the effects of a Mat Pilates training (MPT) regimen on arterial stiffness (pulse wave velocity, PWV), blood pressure (BP), wave reflection (AIx) and endothelial function in obese premenopausal women with elevated BP.

Detailed Description

Using a parallel experimental design, participants were randomly assigned to either MPT (n=14) or non-exercising control group (n=14) for 12 weeks. Participant in the MPT group trained 3 days/week . Participants' brachial to ankle PWV (baPWV), systolic and diastolic BP, AIx, plasma NO levels were measured at baseline and after 20 weeks of their assigned intervention.

Study Timeline

• Study Start: 2018-04-01
• Primary Completion: 2018-10-30
• Study Completion: 2018-10-30
• Study First Submitted: 2019-03-26
• Study First Submitted QC: 2019-04-06
• Study First Posted: 2019-04-09
• Status Verified: 2020-10
• Last Update Submitted: 2020-10-29
• Last Update Posted: 2020-10-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 28

Inclusion Criteria

• body mass index 30-40 kg/m2
• <1 h of regular exercise per week in the previous year
• systolic/diastolic BP: 120-129mm Hg systolic BP and ˂ 80 mm Hg for diastolic BP
• Nonsmokers

Exclusion Criteria

• body mass index ˂30 and ≥40 kg/m2
• chronic diseases
• taking oral contraceptives
• pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Mat Pilates training	Mat Pilates training	The MPT group participated in 3-one hour supervised training sessions per week for 12 weeks. All MP sessions were performed in nonconsecutive days. The MP sessions were divided into the following stages: initial warm up and stretching (10 min), general conditioning consisting of MP exercises (40 min) and stretching and cooling down (10 min). The participants performed 12 basic MP exercises (one set of 6-10 repetitions was performed per exercise). Breathing, a core principle of MP, was performed by forced but controlled inspirations and exhalations, while relaxing and contracting the abdomen, respectively. All sessions were supervised by a certified MP instructor.

Primary Outcome Measures

Name	Time	Method
Arterial Stiffness	12 weeks	via Pulse Wave Velocity

Secondary Outcome Measures

Name	Time	Method
Pressure Wave Reflection	12 weeks	via Augmentation Index
Endothelial Function	12 weeks	via plasma nitric oxide
Systolic and Diastolic Blood Pressure	12 weeks	Automatic BP monitor

Trial Locations

Locations (1)

University of Nebraska; 🇺🇸 Omaha, Nebraska, United States