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Mat Pilates and Vascular Function in Obese Females

Not Applicable
Completed
Conditions
Elevated Blood Pressure
Obese
Registration Number
NCT03907384
Lead Sponsor
Marymount University
Brief Summary

Obesity is associated with progressive decreases in arterial health and function. It is crucial to prevent or reduce the negative effects of aging on the vasculature by implementing appropriate lifestyle interventions, such as exercise training. We examined the effects of a Mat Pilates training (MPT) regimen on arterial stiffness (pulse wave velocity, PWV), blood pressure (BP), wave reflection (AIx) and endothelial function in obese premenopausal women with elevated BP.

Detailed Description

Using a parallel experimental design, participants were randomly assigned to either MPT (n=14) or non-exercising control group (n=14) for 12 weeks. Participant in the MPT group trained 3 days/week . Participants' brachial to ankle PWV (baPWV), systolic and diastolic BP, AIx, plasma NO levels were measured at baseline and after 20 weeks of their assigned intervention.

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
28
Inclusion Criteria
  • body mass index 30-40 kg/m2
  • <1 h of regular exercise per week in the previous year
  • systolic/diastolic BP: 120-129mm Hg systolic BP and ˂ 80 mm Hg for diastolic BP
  • Nonsmokers
Exclusion Criteria
  • body mass index ˂30 and ≥40 kg/m2
  • chronic diseases
  • taking oral contraceptives
  • pregnancy

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Arterial Stiffness12 weeks

via Pulse Wave Velocity

Secondary Outcome Measures
NameTimeMethod
Pressure Wave Reflection12 weeks

via Augmentation Index

Endothelial Function12 weeks

via plasma nitric oxide

Systolic and Diastolic Blood Pressure12 weeks

Automatic BP monitor

Trial Locations

Locations (1)

University of Nebraska

🇺🇸

Omaha, Nebraska, United States

University of Nebraska
🇺🇸Omaha, Nebraska, United States

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