NCT01690039已完成不适用
Comparison of Furosemide/Fludrocortisone With Ammonium Chloride Loading Test in the Diagnosis of Incomplete dRTA in Kidney Stone Formers
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 170
- 试验地点
- 1
- 主要终点
- Capability of urinary acidification
研究概览
简要总结
Purpose
- To compare the performance of the two currently employed urinary acidifications tests in stone formers, the furosemide/fludrocortisone and ammonium chloride loading test.
- To study the impact of polymorphisms in the genes ATP6V1B1, ATP6V0A4 and SLC4A1 on urinary acidification in stone formers.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •One or more episodes of nephrolithiasis
排除标准
- •Absence of informed consent
- •All conditions affecting renal acidification
- •Pregnancy
研究组 & 干预措施
All study participants
Furosemide-Fludrocortisone-Test and Ammonium chloride-Loading Test will be performed in renal stone patients.
干预措施: Furosemide-Fludrocortisone-Test (test for urinary acidification) (Drug)
结局指标
主要结局
Capability of urinary acidification
时间窗: Five to six hours
次要结局
- Polymorphisms in the ATP6V1 gene(12 months)
研究者
研究点 (1)
Loading locations...
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