A COMPARATIVE STUDY TO INVESTIGATE THE EFFECT OF VAMANA KARMA AND TRIPHALA AND GUDUCHI CHURNA WITH MADHU ON GUT MICROBIOTA AND METABOLITE PATTERNS IN PRAMEHA W.S.R TO TYPE 2 DIABETES MELLITUS AND HEALTHY INDIVIDUALS.

All India Institute of Ayurveda0 个研究点目标入组 0 人开始时间: 待定最近更新: 2022年10月17日

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•For Prameha(Type 2 Diabetes Mellitus) Individuals-
•1. BMIÃ¢â?°Â¥ 20
•2. Kaphaj/Kapha-pittaj Vikriti predominant individuals
•3. Diagnosed cases of Prameha/Madhumeha/T2DM with either of the following-
•a) Fasting plasma glucose values of Ã¢â?°Â¥ 7.0 mmol/L (126 mg/dl)
•b) 2-h post-load plasma glucose Ã¢â?°Â¥ 11.1 mmol/L (200 mg/dl)
•c) HbA1c Ã¢â?°Â¥ 6.5% (48 mmol/mol)
•d) Random blood glucose Ã¢â?°Â¥ 11.1 mmol/L (200 mg/dl)
•4. Chronicity: Up to 10 years
•For Healthy Individuals
•1. BMIÃ¢â?°Â¥ 20
•2. Kaphaj/Kapha-pittaj Prakriti predominant Individuals as per Proforma for Prakriti Assessment by CSIR Ayurgenomics Unit- TRISUTRA CSIR-IGIB, NEW DELHI
•3. Healthy individuals as per Proforma for Health Assessment by self-reporting of CSIR Ayurgenomics Unit- TRISUTRA CSIR-IGIB, NEW DELHI

•Patients unfit for Snehana(Internal Oleation), Svedana(Sudation), Vamana(therapeutically induced emesis for internal bio-cleansing).
•For Prameha(Type 2 Diabetes Mellitus)-
•1. Patients with T2 DM exceeding the following plasma glucose limits-
•a) Fasting plasma glucose values of Ã¢â?°Â¥ 300mg/dL
•b) 2-h post-load plasma glucoseÃ¢â?°Â¥400mg/dL
•c) Random blood glucoseÃ¢â?°Â¥ 400mg/dL
•2. Chronicity: More than 10 years.
•3. Known cases of Severe systemic diseases like- Cardiac disease, pulmonary tuberculosis, severe lung disease, uncontrolled diabetes and pregnant women.

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