Dexmedetomidine versus Fentanyl on Intubation Stress Responses in Pre-eclamptic patients undergoing Caesarean delivery.

Not Applicable

Not yet recruiting

• Conditions: Pregnancy and Childbirth; Surgery; pre- eclampsia, caesarean delivery

• Registration Number: PACTR201508001198128
• Lead Sponsor: Rehab Said Elkalla

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2015-07-12
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Pending
• Sex: Female
• Target Recruitment: 80

Inclusion Criteria

women aged ¿ 18 years, with severe pre-eclampsia undergoing elective caesarean deliveries will be enrolled. Pre-eclampsia will be regarded as severe {if the systolic arterial pressure (SAP) on admission exceed 160 mm Hg, the diastolic pressure exceed 110 mm Hg, or both, obtained on at least two separate occasions, or if the patient has symptoms of imminent eclampsia (severe headache, visual disturbance, epigastric pain, hyper-reflexia, or vomiting), and proteinuria on urine dipstick was 3+ or worse}.

Exclusion Criteria

suspected difficult intubation (mallanpati score 3-4), history of exacerbated chronic medical disease, diabetes mellitus, morbid obesity, allergy to drugs used, and known fetal anomalies. Patients will be excluded from analysis if tracheal intubation takes longer than 40 seconds or if more than 1 attempt will be required for successful intubation.

Study & Design

• Study Type: Interventional
• Study Design: Not specified