Sleep, Autonomic Nervous System and Cardiorespiratory Capacity in Autism Spectrum Disorders Children
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Autonomic Nervous System Diseases
- Sponsor
- University Hospital, Grenoble
- Enrollment
- 78
- Locations
- 1
- Primary Endpoint
- sleep evaluation
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
Autism Spectrum Disorders (ASD) is a neurodevelopmental disorder which involves social and behavioural impairments. Autonomic dysfunctions and disturbed sleep were often associated to ASD. The investigators proposed to explore the impact of physical activity on these disorders. In this context, it is necessary to characterize the cardiorespiratory capacities of ASD children in order to promote physical activity for this population. To examine potential differences between ASD and control children, some explorations were proposed: a maximal treadmill test, motor evaluation, and orthostatic test (for the evaluation of autonomic nervous system).
An actimetry during one week (evaluation of physical activity and sleep) completed this study in order to specify sleep characteristic and established the possible link between physical activity sleep characteristics and physical fitness in ASD children.
Investigators
Eligibility Criteria
Inclusion Criteria
- •children physically active
- •children with an intellectual quotient \>70
- •for autism children a diagnosis of autism in accordance to DSMV
Exclusion Criteria
- •history of cardio-vascular disease
- •history of asthma or respiratory disease
- •Behavior disorders.
- •medical treatment by neuroleptic or melatonin or antiepileptic
Outcomes
Primary Outcomes
sleep evaluation
Time Frame: 7 nights
Sleep characteristics are obtained by an actimetry during 7 nights in order to observe sleep disorders. Sleep Questionnaires are also completed.
cardiorespiratory evaluation
Time Frame: 1 day
a maximal treadmill test is proposed (evaluation of : VO² max, maximal heart rate)
autonomic nervous system evaluation
Time Frame: 1 day and 3 nights
an orthostatic test is proposed in order to verify the ANS adaptation. A nocturnal recording is made during three nights in order to verify the possible link between the rest autonomic adaptations and a possible dysautonomia observed with the orthostatic test.
Secondary Outcomes
- Behavioural characteristics(1 hour)
- biological parameters(1 day)
- physical activity(7 days)
- Motor capacities(1 day)