Sleep, Autonomic Nervous System and Cardiorespiratory Capacity in Autism Spectrum Disorders Children
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 78
- 试验地点
- 2
- 主要终点
- sleep evaluation
研究概览
简要总结
Autism Spectrum Disorders (ASD) is a neurodevelopmental disorder which involves social and behavioural impairments. Autonomic dysfunctions and disturbed sleep were often associated to ASD. The investigators proposed to explore the impact of physical activity on these disorders. In this context, it is necessary to characterize the cardiorespiratory capacities of ASD children in order to promote physical activity for this population. To examine potential differences between ASD and control children, some explorations were proposed: a maximal treadmill test, motor evaluation, and orthostatic test (for the evaluation of autonomic nervous system).
An actimetry during one week (evaluation of physical activity and sleep) completed this study in order to specify sleep characteristic and established the possible link between physical activity sleep characteristics and physical fitness in ASD children.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 8 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •children physically active
- •children with an intellectual quotient >70
- •for autism children a diagnosis of autism in accordance to DSMV
排除标准
- •history of cardio-vascular disease
- •history of asthma or respiratory disease
- •Behavior disorders.
- •medical treatment by neuroleptic or melatonin or antiepileptic
结局指标
主要结局
sleep evaluation
时间窗: 7 nights
Sleep characteristics are obtained by an actimetry during 7 nights in order to observe sleep disorders. Sleep Questionnaires are also completed.
cardiorespiratory evaluation
时间窗: 1 day
a maximal treadmill test is proposed (evaluation of : VO² max, maximal heart rate)
autonomic nervous system evaluation
时间窗: 1 day and 3 nights
an orthostatic test is proposed in order to verify the ANS adaptation. A nocturnal recording is made during three nights in order to verify the possible link between the rest autonomic adaptations and a possible dysautonomia observed with the orthostatic test.
次要结局
- Behavioural characteristics(1 hour)
- biological parameters(1 day)
- physical activity(7 days)
- Motor capacities(1 day)