A Study to Compare Mycophenolate Mofetil and Tacrolimus in the Treatment of Membranous Lupus Nephritis

Phase 3

Completed

• Conditions: Lupus Nephritis; Glomerulonephritis, Membranous

• Registration Number: NCT00404794
• Lead Sponsor: Hospital Authority, Hong Kong

Brief Summary

This is a prospective randomized open-label pilot study to compare mycophenolate mofetil in combination with corticosteroid treatment and tacrolimus in combination with corticosteroid treatment in membranous lupus nephritis. The change in urine protein excretion will be the primary outcome studied. The study duration will be 24 months for each patient.

Detailed Description

Not available

Study Timeline

• Study Start: 2005-11
• Study First Submitted: 2006-11-27
• Study First Submitted QC: 2006-11-27
• Study First Posted: 2006-11-29
• Study Completion: 2009-10
• Status Verified: 2013-10
• Last Update Submitted: 2013-10-22
• Last Update Posted: 2013-10-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• abnormal urine protein excretion and biopsy-proven membranous lupus nephritis

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Proteinuria

Secondary Outcome Measures

Name	Time	Method
Adverse effects

Trial Locations

Locations (1)

Queen Mary Hospital; 🇨🇳 Hong Kong, China