Water Exercise and Vascular Function in Elderly

Not Applicable

Completed

• Conditions: Elderly Women
• Interventions: Other: Educational lectures; Other: Exercise

• Registration Number: NCT01642654
• Lead Sponsor: Universidade Federal do Rio Grande do Norte

Brief Summary

Objectives:

The purpose of this research was to assess modifications caused by a concurrent water exercise program on plasma nitrite (NO3), cerebral vascular resistance and cholesterol in the elderly and analyze the correlations between these variables after intervention.

Methods The sample was composed of 40 women mean age 69,21 ±5,27 years old, divided into an intervention (WG) and control group (CG). It was to measure nitrite concentration (NO3) by the Griess reaction; internal cerebral arteries were assessed by Doppler ultrasound to determine the resistivity index and Cholesterol was determined using the colorimetric enzymatic method and test kit. Intervention with water exercise program consisted of three weekly sessions for 16 weeks.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-05
• Primary Completion: 2010-09
• Study Completion: 2010-09
• Status Verified: 2012-03
• Study First Submitted: 2012-07-10
• Study First Submitted QC: 2012-07-16
• Last Update Submitted: 2012-07-16
• Study First Posted: 2012-07-17
• Last Update Posted: 2012-07-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 40

Inclusion Criteria

• older than 60 and lass than 80 years age;
• the elderly should be independent in their ADLs;
• be considered able for medical evaluation to participate in the intervention and testing protocols;
• still not be participating in regular systematized physical activity for at least six months.

Exclusion Criteria

• subjects with any form of transmittable or uncontrolled disease or insulin-dependent hypertensive;
• unable to perform functional autonomy tests;
• women undergo hormonal replacement therapy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Control	Educational lectures	-
Treatment	Exercise	-

Primary Outcome Measures

Name	Time	Method
Determining modifications caused by this program on plasma nitrite concentration (NO3).	16 weeks	For NO analysis, serum was separated from the erythrocyte mass. The material was centrifuged in a SIGMA 4k15 centrifuge at 3500 rpm and 18° for 10 minutes (LANEX laboratory- UFPI); the serum was then pipetted and frozen at 80° for evaluation after retesting (16 weeks). NO production was determined based on NO3 in the supernatant of cultured cells, an indirect measurement of NO synthesis.

Secondary Outcome Measures

Name	Time	Method
Cerebral artery assessment	16 weeks	Carotid and vertebral arteries were assessed by Doppler ultrasound, with GE Logiq 5 equipment and multi-frequency linear transducer (Milwaukee - UEA). Parameters used were evaluation of peak systolic velocity and end-diastolic velocity of the common carotid and left and right internal carotids, with the angle of insonation corrected to 60°. The resistivity index of arteries was calculated, resulting from the mathematical formula in centimeters per second (cm/s): Resistivity index = Peak systolic velocity - End-diastolic velocity / Peak systolic velocity.

Trial Locations

Locations (1)

Universidade Estadual do Piauí; 🇧🇷 Teresina, PI, Brazil