Ebola Vaccine Ring Vaccination Trial in Guinea
Not Applicable
- Conditions
- Ebola Virus Disease
- Registration Number
- PACTR201503001057193
- Lead Sponsor
- World Health Organization
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 21500
Inclusion Criteria
Individuals aged 18 years or older who live in the defined vaccination ring
Children 6 to 17 years following results from phase 2 study in Gabon, and following DSMB recommendation (3 July 2015)
Exclusion Criteria
History of EVD (self-report or laboratory confirmed).
Pregnancy (verbal report) or breast-feeding. Women will be offered, but not required to take, a pregnancy test.
History of having received other investigational research agents in the previous 28 days.
Self- report of clinically important immunodeficiency condition, e.g. HIV/AIDS.
History of anaphylaxis to a vaccine or vaccine component
Severe illness that makes the person bed-bound or requiring hospitalization at the time of the vaccination.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Any probable or supsected case from which a blood sample taken is laboratory confirmed as positive for EVD, or any deceased individual with probable EVD, from which a post-mortem sample taken within 48 hours after death is laboratory confirmed as positive for Ebola Virus Disease
- Secondary Outcome Measures
Name Time Method Incidense of Serious Adverse Events