Are macrolide antibiotics effective in chronic idiopathic cough?
Phase 3
Completed
- Conditions
- Chronic idiopathic coughSigns and SymptomsCough
- Registration Number
- ISRCTN75749391
- Lead Sponsor
- niversity of Nottingham (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Non-smoking subjects aged 18 to 80 years (either sex) with idiopathic cough for at least 2 months
Exclusion Criteria
1. Active smoking or smoking history in excess of 20 pack years
2. Non-idiopathic cough or other major co-morbidity including abnormal liver function tests
3. Medication known to interact with azithromycin
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method eicester Cough Questionnaire score, measured after 8 weeks' treatment with azithromycin or placebo
- Secondary Outcome Measures
Name Time Method 1. Cough severity score<br>2. Adverse effects<br>Measured at study visits after 4 weeks, 8 weeks and 12 weeks