Are macrolide antibiotics effective in chronic idiopathic cough? - MAC
Phase 1
- Conditions
- idiopathic chronic cough, defined as cough with no identifiable cause and which has been present for at least 2 monhs.MedDRA version: 9.1 Level: LLT Classification code 10011224 Term: Cough
- Registration Number
- EUCTR2008-004143-11-GB
- Lead Sponsor
- The University of Nottingham
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
Adults with cough for greater than 2 months after exclusion of other common causes of cough (asthma, eosinophilic bronchitis, gastroeosophogeal reflux and upper airway syndrome).
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
Active smoking or smoking history in excess of 20 pack years.
Non-idiopathic cough or other major co-morbidity including abnormal liver function tests
Taking medication known to interact with azithromycin (cylcosporin, terfenadine, theophylline and warfarin).
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method