Effect of autologe PRP with hyaluronic acid on knee osteoarthritis
Phase 3
- Conditions
- Knee osteoarthritis.Primary gonarthrosis, bilateral
- Registration Number
- IRCT2015041121697N1
- Lead Sponsor
- Vice-chancellor for research, School of Medicine, Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 76
Inclusion Criteria
Chronic pain or swelling for at leas 4 months before radiological findings; degenerative changes in radiology
Exclusion criteria:
Systemic disorders like diabetes, rheumatoid arthritis; varus or valgus in spine more than 5 degree; hematologic disorders; chronic heart diseases; infections; immune compromise; hemoglobin less than 11; platelet less than 150000; incomplete questionnaire; incomplete treatment course; no interest to participate; multi-arthritis; intra-articular injection of hyaloronic acid in last 6 months; intra-articular injection of steroid in last 3 months
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Knee pain. Timepoint: 0, 2 and 6 monts after injection. Method of measurement: WOMAC questionnaire.;Knee pain. Timepoint: 0, 2 and 6 monts after injection. Method of measurement: VAS questionnaire.;Knee stiffnes. Timepoint: 0, 2 and 6 monts after injection. Method of measurement: WOMAC questionnaire.;Knee function. Timepoint: 0, 2 and 6 monts after injection. Method of measurement: WOMAC questionnaire.
- Secondary Outcome Measures
Name Time Method Septic arthritis. Timepoint: 2 weeks after injection. Method of measurement: Inspection.