Comparison Of Efficacy Of Different Treatment Regimens In Pulmonary Artery Hypertension Secondary To Lung Disease And/Or Hypoxia
Phase 3
- Conditions
- Health Condition 1: null- Pulmonary artery hypertension secondary to lung disease and/or hypoxia
- Registration Number
- CTRI/2011/09/001992
- Lead Sponsor
- Dr SK Sharma
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 45
Inclusion Criteria
?Pulmonary artery hypertension diagnosed by doppler echocardiography as mean pulmonary artery pressure 25 mmHg (done in department of cardiology, AIIMS)
?Age more than 18 years
?Pulmonary artery hypertension due to hypoxia, either chronic obstructive airway disease or diffuse pulmonary lung disease
?Willing to consent to participate in the trial
?WHO functional class I,II, III
Exclusion Criteria
?WHO functional class IV
?Patient participating in any other trial
?Concomitant coronary artery disease
?Nitrate intake
?Liver dysfunction
?Pregnancy and lactation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Following parameters at 6 months <br/ ><br>?WHO functional classification <br/ ><br>?6 minute walk test <br/ ><br>?Pulmonary function test <br/ ><br>?Visual analog scale for dyspnea <br/ ><br>?Echocardiography measuring pulmonary artery pressure <br/ ><br>Timepoint: Following parameters at 6 months <br/ ><br>?WHO functional classification <br/ ><br>?6 minute walk test <br/ ><br>?Pulmonary function test <br/ ><br>?Visual analog scale for dyspnea <br/ ><br>?Echocardiography measuring pulmonary artery pressure <br/ ><br>
- Secondary Outcome Measures
Name Time Method Following parameters at 3 months <br/ ><br>?WHO functional classification <br/ ><br>?6 minute walk test <br/ ><br>?Pulmonary function test <br/ ><br>?Visual analog scale for dyspnea <br/ ><br>?Echocardiography measuring pulmonary artery pressure <br/ ><br>?Biochemical markers and at 6 months <br/ ><br>Timepoint: 3 months