A clinical trial to study the effects of two different protocols of cetrorelix injection timings in IUI cycles in infertile wome
Not Applicable
Completed
- Conditions
- Health Condition 1: null- Infertility
- Registration Number
- CTRI/2014/12/005289
- Lead Sponsor
- ot applicable
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 45
Inclusion Criteria
1)Unexplained infertility;
2)Mild male factor infertility;
3)Ovulation dysfunction infertility with previously failed induction with letrozole or clomiphene;
4)At least one patent fallopian tube;
5)BMI 18.5â??29.9 kg/m2
6)Euthyroid state
7)No associated medical problems like diabetes mellitus or Hypertension or Drug allergies.
Exclusion Criteria
1)Severe male factor infertility;
2)Stage III or IV endometriosis;
3)Tubal Factor Infertility;
4)baseline FSH >12 IU/L;
5)Less than four antral follicles per ovary
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Premature luteinization rate <br/ ><br>2.Ovulation ratesTimepoint: 1. If LH more than 10 mIU/ml and Progesterone more than 2ng/ml on day 10 and/or day 12 of menstrual cycle <br/ ><br>2. Documented by transvaginal ultrasound after 36 hours of ovulation trigger
- Secondary Outcome Measures
Name Time Method 1.Pregnancy rate <br/ ><br>2.Endometrial thickness <br/ ><br>3.Adverse effects like ovarian hyperstimulation syndrome and multiple pregnancies <br/ ><br>4.Cycle cancellation rate <br/ ><br>Timepoint: 1.Positive urine pregnancy test after 15 days of IUI <br/ ><br>2.Thickness measurement on the day of dominant follicle (more than or equal to 18 mm size) <br/ ><br>3.Checked on the day of positive urine pregnancy test or in a symptomatic patient <br/ ><br>4.If no dominant follicle by day 18 of the cycle