Clinical trial to Compare the efficacy of two different doses of sugammadex for reversal of vecuronium induced neuromuscular blockage in patients posted for elective surgeries under general anesthesia
Phase 4
- Conditions
- Health Condition 1: 8- Other Procedures
- Registration Number
- CTRI/2024/08/071853
- Lead Sponsor
- GOVERNMENT MEDICAL COLLEGE BHAVNAGAR
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1 Age 18 to 60 years
2 ASA grade 1 to 3
3 schedule for elective surgery under general anesthesia
4 Surgery duration less than 2 hours
5 BMI less than30
Exclusion Criteria
Suspected difficult intubation
Significant hepatic and renal dysfunction
Any suspected neuromuscular disorder
Known or suspected family history of malignant hyperthermia
Lactating or pregnant female
Study & Design
- Study Type
- PMS
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare clinical recovery profile of two different dose of sugammadex in terms of time require for spontaneous eye opening, adequate tidal volume (5ml/kg) , hand grip for 5 seconds and time requires for extubation. <br/ ><br>Timepoint: At baseline,Immediate after Inj.sugammadex and after 5min,10min,15min,30min,60min,90 min,120min after Inj.sugammadex
- Secondary Outcome Measures
Name Time Method 1. To compare the hemodynamic changes(Mean arterial pressure, Heart rate) after Inj. sugammadex <br/ ><br> 2. Side effects (If any) after Inj. sugammadex in both groups. <br/ ><br>Timepoint: At baseline,Immediate after Inj.sugammadex & after 5min,10min,15min,30min,60min,90 min,120min after Inj.sugammadex