To study the effect of two different doses of oral melatonin on post-operative cognitive dysfunction in elderly patients after surgery under regional anesthesia
Phase 1
- Conditions
- Health Condition 1: G968- Other specified disorders of central nervous system
- Registration Number
- CTRI/2021/08/035467
- Lead Sponsor
- Department of Anesthesiology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
patients given written informed consent will be taken
age 60 years
male and female
All patients under regional anaesthesia
ASA grade I, II and III
Exclusion Criteria
any comorbidities
dementia
not given consent
age >60 years
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mini mental state examination score, subjective sleep quality and general well beingTimepoint: Pre operatively, at day 1, day3,day7 and 3months after surgery
- Secondary Outcome Measures
Name Time Method changes in POCD scoreTimepoint: 1-2hrs