Quantitative fMRI-imaging study of cerebral pathways during movement to music in patients with Parkinson’s Disease
- Conditions
- G20Parkinson disease
- Registration Number
- DRKS00009986
- Lead Sponsor
- Klinik für Neuroradiologie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 20
Patients:
Patients over 18 with idiopathic Parkinson's Syndrome of the akinetic-rigid type.
Signed consent.
Healthy controls:
Neurologically healthy individuals matched for age, sex and dominant hand.
Signed consent.
Patients:
(i) Contraindications for MRI scans (see also MRI information sheet), (ii) inappropriate physical conditions which prohibit a 30 - 45 minute MRI scan, (iii) brain pathologies such as history of stroke, severe cerbral microangiopathy, tumors, inflammation, (iv) pregnancy, (v) patients with Deep Brain Stimulation.
Healthy controls:
(i) Contraindications for MRI scans (see also MRI information sheet), (ii) inappropriate physical conditions which prohibit a 30 - 45 minute MRI scan, (iii) brain pathologies such as history of stroke, severe cerbral microangiopathy, tumors, inflammation, (iv) pregnancy, (v) Parkinson's Disease vi) Parkinsonoid symptoms.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <br>Assessment of difference in cerebral activity during movement to music, to rhythm and in silence in people with Parkinson's Disease. These differences in cerebral activity result in changes to the fMRI-signal which can be measured.
- Secondary Outcome Measures
Name Time Method <br><br>The differences in cerebral activity to rhythm, music and in silence correlate with the patient's movement to rhythm, music and in silence, respectively.<br>The amplitude and frequency of the movement (i.e. the opening and closing of the fist) is measured via a pressure sensor which the patient/ healthy control holds in their hand throughout the entire procedure.