MAGNESIUM & SSRI VS SSRI ALONE AMONG PATIENTS OF MAJOR DEPRESSIVE DISORDER
试验速览
- 阶段
- 2 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Change in severity of depressive symptoms
研究概览
简要总结
Role of Magnesium in Depressive Disorder
详细描述
Because of the significant role that magnesium serves in mood regulation, the goal of this study is to evaluate the impact of starting the therapy of major depressive disorder with a combination of SSRI and Mg, as well as SSRI alone.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients of above 18 years diagnosed with DSM who had MDD and receiving SSRI alone and SSRI plus magnesium.
排除标准
- •Individuals who recently underwent treatment with electroconvulsive therapy, have a history of epilepsy or other severe neurological problems, have experienced a head injury, are cognitively impaired, and have comorbid conditions such as liver, renal, cardiovascular, neurological, or endocrine, or respiratory problems, or are pregnant or nursing mothers
研究组 & 干预措施
Interventional Arm
Patients in this group will be treated with SSRI and magnesium therapy for four weeks
干预措施: Use of magnesium with SSRI (Drug)
Placebo
Patients in this group will be treated with SSRI as a placebo in interventional treatment.
干预措施: SSRI (Drug)
结局指标
主要结局
Change in severity of depressive symptoms
时间窗: Four Weeks
Change in severity of depressive symptoms, measured by the difference in mean scores on the Beck Depression Inventory-II (BDI-II) from baseline to 4 weeks post-intervention
次要结局
未报告次要终点
研究者
Ahmad Yar
Dr Ahmad Yar
University of Child Health Sciences and Children's Hospital, Lahore