A comparative study of Magnesium Sulphate versus Dexamethasone as an adjuvant to bupivacaine in ultrasound-guided transversus abdominis plane block in patients undergoing lower abdominal surgeries
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- A comparative study of magnesium sulphate versus dexamethasone as an adjuvant to bupivacaine in ultrasound-guided transversus abdominis plane block in patient undergoing lower abdominal surgeries
研究概览
简要总结
It is a prospective, comparative, randomized, double blinded study to compare magnesium sulphate versus dexamethasone as an adjuvant to 0.25% bupivacaine in ultrasound-guided transversus abdominis plane block in patients undergoing lower abdominal surgeries. the parameters that will be assessed include quality of block, duration of block, timely post operative pain scores, time to rescue analgesia and total number of analgesics given in 24 hours
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant, Investigator, Outcome Assessor and Date-entry Operator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA grade I or II fit patients, 2)Ages between 18 and 65 years, 3) Patients undergoing lower abdominal surgeries under spinal anaesthesia, 4) Hemodynamically stable patients with all routine investigations within normal limits without any other co-morbidities, 5)Patients who are not on any cardiac related drugs, 6) Availability of written informed consent from concerned patient.
排除标准
- •Patients not willing to participate in this study, 2)Patients with ASA physical status III and above physical status, 3)Patients less than 18 years and above 65 years of age, 4)Patients with uncontrolled systemic disorders like neurological, cardiac, metabolic, renal, pulmonary disorders, hepatic disease with coagulation abnormalities etc, 5)Patients on calcium channel blocker, 6)Patients having local infection at the site where needle for block was to be inserted, 7)Patients with contraindication for spinal anaesthesia, 8)Patients with bleeding or coagulation disorders, 9)Patients with known allergies to the study drugs, 10)Patients with weight less than 40 kgs and height less than 140 cms.
结局指标
主要结局
A comparative study of magnesium sulphate versus dexamethasone as an adjuvant to bupivacaine in ultrasound-guided transversus abdominis plane block in patient undergoing lower abdominal surgeries
时间窗: After administration of the block, pain scores will be assessed in both the groups in less than 5 minutes after giving block, after 2 hours, after 4 hours, after 6 hours, after 12 hours, after 16 hours, after 20 hours, and after 24 hours will be assessed
次要结局
- A comparative study of magnesium sulphate & dexamethasone as an adjuvant to bupivacaine in ultrasound-guided transversus abdominis plane block in patient undergoing lower abdominal surgeries(Duration of analgesia will be assessed post giving block after surgery & time to rescue analgesia will be assessed)
研究者
Jekha Mary Babu
Dr. D. Y. Patil Medical College, Hospital and Research Centre