Prevention of hypotension due to spinal anaesthesia and tourniquet release by using intravenous nor adrenalin infusion.
Not Applicable
Completed
- Registration Number
- CTRI/2020/05/025133
- Lead Sponsor
- izams Institute of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 70
Inclusion Criteria
Adult patients of ASA I class (American society of Anaesthesiology), in age group of 18 to 55 years and those assigned for elective, lower limb surgery under only spinal anaesthesia and requiring use of tourniquet will be included.
Exclusion Criteria
Patients need to be excluded will be-
1.ASA II to IV
2.Multiple comorbidities
3.Patients with hypertension and diabetes, morbid obesity
4.Patients on cardiovascular medications including calcium channel blockers, angiotensin convertase inhibitors, Beta or a blocking drugs.
5.Patients with arterial disease
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary outcome: the study primary outcome targets prevention and/or amelioration of the hypotension induced by SAB and tourniquet releaseTimepoint: starting of spinal anaesthesia to 10 min after stoppage of nor epinephrin infusion .
- Secondary Outcome Measures
Name Time Method : this included proper adjustment of rate and duration of infusion to obtain minimal intraoperative heart rate and blood pressure fluctuation, and minimising other manifestations of SAIH (Spinal anaesthesia Induced Hypotension) such as nausea and vomiting during surgery.Timepoint: Following spinal anaesthesia and continued till 10 minutes after tourniquet release, Infusion doses will be tapered gradually and blood pressure readings will be noted for 10 minutes after stoppage.