Hemostatic Profile of Post COVID-19/Long COVID-19 Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 102
- 试验地点
- 1
- 主要终点
- ClotPro FIBTEST
研究概览
简要总结
The present study aims at assessing long-term hemostatic profile of patients recovered from COVID-19 acute infection that remain asymptomatic (POST-COVID) versus patients with residual symptoms (LONG-COVID) through the employment of a commercially available new generation point-of-care viscoelastic device. The primary endpoint is based upon the hypothesis that patients with residual symptoms maintain an abnormal coagulation profile even after recovery from COVID-19.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age > 18 years;
- •recovery from acute COVID-19 infection;
- •COVID-19 pneumonia that required hospitalization in our Institution;
- •discharge from the hospital minimum 3 months before the day of the visit;
- •written consent to participate to the study.
排除标准
- 未提供
结局指标
主要结局
ClotPro FIBTEST
时间窗: Day of the visit
Fibrinogen contribution to the overall clot strength as measured by the ClotPro (maximum clot firmness, MCF, millimeters)
ClotPro INTEST
时间窗: Day of the visit
Intrinsic pathway of the coagulation as measured by the ClotPro (coagulation time CT, seconds; maximum clot firmness, MCF, millimeters)
ClotPro TPATEST
时间窗: Day of the visit
Resistance to the fibrinolysis induced by the tPA (tissue plasminogen) as measured by the ClotPro (lysis time, LT, seconds; maximum lysis, ML, %).
ClotPro EXTEST
时间窗: Day of the visit
Extrinsic pathway of the coagulation as measured by the ClotPro (coagulation time CT, seconds; maximum clot firmness, MCF, millimeters)
次要结局
未报告次要终点
研究者
Marco Ranucci
Dr
IRCCS Policlinico S. Donato