Compliance and Tolerance to Oral AntiBiotherapy in Osteoarticular Infections
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Percentage of doses taken at 6 weeks
研究概览
简要总结
Bone and joint infections (BJI) are most often bacterial infections that can occur after surgery or de novo. They are rarely fatal in the short term, but are associated with significant morbidity, impaired quality of life and significant costs. Treatment of BJI is based on antibiotic therapy, often combined with surgery. Antibiotic therapy, at high doses, lasts a minimum of 6 weeks. It can be responsible for severe adverse effects. These characteristics (prolonged duration, multiple daily doses, and adverse effects) are known to negatively affect treatment adherence in general.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •≥ 18 years
- •Diagnosis of osteoarticular infection
- •Treatment with at least one oral antibiotic for a minimum expected duration ≥ 6 weeks with an expected end of treatment date
- •Patient who was informed and did not object to participate in the study
排除标准
- •Treatment for BJI with oral antibiotic without end of treatment date
- •treatment for BJI with parenteral antibiotic only
- •patient who doesn't have a telephone number or who doesn't want to give it
- •Adults subject to a legal protection measure
- •Pregnant or breastfeeding women
结局指标
主要结局
Percentage of doses taken at 6 weeks
时间窗: At 6 weeks after surgery
Ratio of the number of doses taken over the theoretical number of doses to be taken over the period
Percentage of doses taken at 3 months
时间窗: at 3 months after surgery
Ratio of the number of doses taken over the theoretical number of doses to be taken over the period
次要结局
未报告次要终点