D-dimer Assay for the Exclusion of Intra-atrial Thrombus Risk Before Ablation of Atrial Fibrillation
- Conditions
- Atrial Fibrillation
- Interventions
- Other: D-dimer assay before ablation of atrial fibrillation
- Registration Number
- NCT02199080
- Lead Sponsor
- Groupe Hospitalier de la Rochelle Ré Aunis
- Brief Summary
The purpose of this study is to determine whether D-dimer dosage allow to exclude risk of intraatrial thrombus before performing an ablation of atrial fibrillation
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 2506
- Age> 18 years.
- Patients hospitalized for ablation of atrial fibrillation or symptomatic left flutter
- Patient informed of the study
- Age <18 years.
- Patients under guardianship
- Pregnant woman
- Contraindication to transesophageal echocardiography
- transesophageal echocardiography made in another center as the center of ablation
- Refusal of the patient to participate in the study
- Patient participating in another interventional study in which an intervention related to biomedical research is performed before the transesophageal echocardiography
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Atrial fibrillation D-dimer assay before ablation of atrial fibrillation D-dimer assay before ablation of atrial fibrillation
- Primary Outcome Measures
Name Time Method Number of Patients With Atrial Thrombus Diagnosed by Transoesophageal Ultrasound up to 48 hours before ablation
- Secondary Outcome Measures
Name Time Method Risk Factors 48 hours before ablation variables related to the presence of atrial thrombus
Atrial Thrombus Exclusion (ATE) Score 48 hours before ablation The following thromboembolic risk factors mark 1 point if present in patient:
* hypertension = 1 point
* cardiac insufficiency = 1 point
* history of stoke = 1 point
* d-dimer level \>270ng/mL = 1 point The sum corresponds to the ATE scoreCHADS2 Score 48 hours before ablation CHADS2 score (congestive heart failure=1, hypertension=1, diabetes mellitus=1, history of stroke or transient ischemic attack=1, and age under 75=1)
Trial Locations
- Locations (37)
Service de cardiologie, CH Avignon
🇫🇷Avignon, France
Service de cardiologie, AP Hôpital Henri Mondor
🇫🇷Créteil, France
Clinique La Fourcade
🇫🇷Bayonne, France
Service de cardiologie, CHU Dijon
🇫🇷Dijon, France
Groupe Hospitalier de la Rochelle Ré Aunis
🇫🇷La Rochelle, France
Service de cardiologie, CHU Bordeaux
🇫🇷Bordeaux, France
Service de cardiologie, CHU Limoges
🇫🇷Limoges, France
Service de cardiologie, HCL Groupement Est
🇫🇷Lyon, France
Service de cardiologie, APM Hôpital de La Timone
🇫🇷Marseille, France
Service de cardiologie, CHI Aix Pertuis CHPA-CHIAP
🇫🇷Marseille, France
Service de cardiologie, CHI Le Raincy Montfermeil
🇫🇷Montfermeil, France
Service de cardiologie, CHU Nancy
🇫🇷Nancy, France
Service de cardiologie, CHU Nîmes
🇫🇷Nîmes, France
Service de cardiologie, HP Les Franciscaines
🇫🇷Nîmes, France
Service de cardiologie, AP Hôpital la Pitié Salpêtrière
🇫🇷Paris, France
Service de cardiologie, CHU Poitiers
🇫🇷Poitiers, France
Service de cardiologie, CHU Caen
🇫🇷Caen, France
Service de cardiologie, CHU Clermont Ferrand
🇫🇷Clermont Ferrand, France
Centre Hospitalier d' Auxerre
🇫🇷Auxerre, France
Service de cardiologie, CHU Brest
🇫🇷Brest, France
Service de cardiologie, CH de la Région d'Annecy
🇫🇷Annecy, France
Service de cardiologie, Hôpital Saint Joseph
🇫🇷Marseille, France
Service de cardiologie, Institut Mutualiste Montsouris
🇫🇷Paris, France
Service de cardiologie, Centre Cardiologique du Nord
🇫🇷Saint Denis, France
Service de cardiologie, Clinique Saint Gatien
🇫🇷Tours, France
Service de cardiologie, CHU Saint Etienne
🇫🇷Saint Etienne, France
Service de cardiologie, Clinique Saint Joseph
🇫🇷Trélaze, France
Service de cardiologie, CHU Toulouse Hôtel Dieu St Jacques
🇫🇷Toulouse, France
Service de cardiologie, Polyclinique Vauban
🇫🇷Valenciennes, France
Service de cardiologie, CH Le Mans
🇫🇷Le Mans, France
Service de cardiologie, Institut Jacques Cartier
🇫🇷Massy, France
Service de cardiologie, CHR Metz Thionville
🇫🇷Metz, France
Service de cardiologie, Nouvelles Cliniques Nantaises
🇫🇷Nantes, France
Service de cardiologie, Groupe Hospitalier Bichat Claude Bernard
🇫🇷Paris, France
Service de cardiologie, CH Pau
🇫🇷Pau, France
Service de cardiologie, CHU Rennes
🇫🇷Rennes, France
Service de cardiologie, CHU Rouen
🇫🇷Rouen, France