Evaluating the Association of Addictions Neuroclinical Assessments based Measures with Treatment Outcomes and their Change following Virtual Reality Cue Exposure In Individuals with Alcohol Use Disorder
试验速览
- 阶段
- 1 期
- 状态
- 尚未招募
- 入组人数
- 50
- 试验地点
- 1
研究概览
简要总结
This study is a prospective pretest-post test control group design to examine the association of Addictions Neuroclinical Assessment (ANA) based measures with treatment outcomes in Alcohol Use Disorder (AUD) after a Virtual Reality Cue Exposure (VRCE) intervention. Fifty inpatients with AUD admitted to the Psychiatry Ward at AIIMS Bhopal will be recruited using purposive sampling and randomly allocated to either a Virtual Reality Cue Exposure (VRCE) + Treatment as usual (TAU) control group. After stabilization patients will complete baseline behavioural tasks and self report measures. VRCE intervention will be given to experiment group and TAU to control group. Follow up measures will be conducted 4 weeks post discharge. Change in results of ANA measures will be compared pre and post intervention as well as its effect on treatment outcomes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 25.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- Male
入选标准
- •Diagnosis of Alcohol Use Disorder (AUD) as per DSM-5 criteria, Currently admitted to the inpatient psychiatry unit at AIIMS Bhopal, Able to understand instructions and perform computerized tasks in Hindi or English, None or mild alcohol withdrawal at the time of assessment Willing and able to provide written informed consent, Willing and eligible for disulfiram as a pharmacological treatment at the time of discharge.
排除标准
- •Comorbid psychiatric disorders (e.g., schizophrenia, bipolar disorder) or other substance use disorders, excluding nicotine
- •Comorbid neurological conditions that interfere with computerized assessment or VR use (e.g., epilepsy, traumatic brain injury, seizure disorders)
- •Severe cognitive impairment (as determined by clinical judgment or documented history) that prevents meaningful task engagement
- •Visual or motor impairments that limit the ability to interact with computerized or VR-based tasks
- •Current use of medications or medical conditions that may significantly affect cognitive functioning (e.g., delirium, heavy sedation)
- •History of severe motion sickness/vertigo, severe migraine triggered by visual stimuli.
研究者
Dr Vijender Singh
AIIMS Bhopal