A comparative study to evaluate the efficacy of dexmedetomidine as a hypotensive agent in comparison to esmolol in ASA grade 1-2 patients undergoing ENT surgeries.

Dr Shilpa bansal1 个研究点分布在 1 个国家目标入组 60 人开始时间: 2017年1月4日最近更新: 2017年2月27日

试验速览

阶段: Phase 3 4
状态: 尚未招募
发起方
入组人数: 60
试验地点: 1
主要终点: primary outcome is to compare the quality of the surgical field using a predefined category scale

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

This study is a prospective, randomised ,double blind, parallel group with active controlled trial to comparethe efficacy and safety of dexmedetomidine with Esmolol as a hypotensive agent in 60 (30 in each group) ASA grade I-II patients of both sexes aged between 18-60 yrs, undergoing Otorhinolaryngeal (ENT) surgeries with attention on theamount of blood loss, quality of the surgical field as primary outcome measures and analgesia requirement, recovery profile, andtolerability in adult patients as secondary outcome measures.

研究设计

研究类型: Interventional
分配方式: Computer generated randomization
盲法: Participant and Outcome Assessor Blinded

入排标准

年龄范围: 18.00 Year(s) 至 60.00 Year(s)（—）
性别: All

入选标准

•Patients aged 18- 60 yrs of both the sexes, undergoing planned Otorhinolaryngeal (ENT) surgeries with ASA grade I-II.

排除标准

•1.Patients refusing to give informed consent.
•2.Patients with recurrent sinus surgery and patients with systemic co-morbidities like hypertension, coronory artery disease, renal or hepatic disease, cerebro vascular accidents.
•3.Patients with coagulopathies or receiving drugs which have effects on coagulation profile.

结局指标

主要结局

primary outcome is to compare the quality of the surgical field using a predefined category scale

时间窗: surgical field score

次要结局

compare the efficacy and safety of dexmedetomidine with Esmolol as a hypotensive agent in ENT surgeries with attention on analgesia requirement, recovery profile, and tolerability in adult patients.(sedation score, visual analogue score, modified aldrete score)

研究者

发起方

Dr Shilpa bansal

申办方类型

Private medical college

研究点 (1)

Loading locations...

相似试验

尚未招募

4 期

A clinical trial to compare the effects of two drugs, dexmedetomidine , a drug used in treatment of raised blood pressure and paracetamol , a drug used for pain relief in patients undergoing laparoscopic cholecystectomy.

CTRI/2022/10/046735DrGadde Venkata Harshitha105

尚未招募

2/3 期

The study between Nidhigdhikadi syrup and Brihati syrup in dry cough

CTRI/2023/11/059747D chandrashekar60

尚未招募

1 期

Effects of Ultrasound and Fluoroscopy guided injection in Ankylosing Spondylitis and related diseases.

CTRI/2020/07/026854R G Kar Medical College and Hospital52

已完成

3 期

A clinical trial to study the effects of artesunate - lumefantrine combination and artemether - lumefatrine combination in the treatment of uncomplicated Plasmodium falciparum malaria.

CTRI/2009/091/000434Ipca Laboratories Limited176

尚未招募

3 期

Effectiveness of homoeopathic medicines in cases of nasal polyp

CTRI/2024/05/066813Dr M P K Homoeopathic Medical College Hospital And Research Centre