COMPARISON OF PREOPERATIVE NEBULIZATION WITH DEXAMETHASONE VERSUS KETAMINE TO PREVENT POST OPERATIVE SORE THROAT IN PATIENTS UNDERGOING GENERAL ANAESTHESIA WITH ENDOTRACHEAL INTUBATION:A RANDOMISED DOUBLE BLIND STUDY.

Dr KUDARY NEETHI PRIYANKA1 个研究点分布在 1 个国家目标入组 150 人开始时间: 2023年11月9日最近更新: 2023年8月29日

试验速览

阶段: 不适用
状态: 尚未招募
发起方
入组人数: 150
试验地点: 1
主要终点: To compare the effectiveness of preoperative nebulization of Dexamethasone for prevention of POST in patients undergoing general anaesthesia with endotracheal intubation.

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

It is a randomized, prospective, comparative, double binded, observational study where preoperative nebulization with dexamethasone and preoperative nebulization with ketamine are compared to reduce post operative sore throat in patients undergoing general anaesthesia with endotracheal intubation.

研究设计

研究类型: Interventional
分配方式: Computer generated randomization
盲法: Participant and Investigator Blinded

入排标准

年龄范围: 18.00 Year(s) 至 60.00 Year(s)（—）
性别: All

入选标准

•1.Patients aged between 18 to 60 years
•American Society of Anaesthesiology (ASA) grade I and II
•Hemodynamically stable patients with all routine investigations within the normal limits requiring GA with endotracheal intubation.

排除标准

•Patient with a history of pre operative upper respiratory tract infection
•History of asthma, recent use of non-steroidal anti inflammatory drugs
•Undergoing head and neck surgeries, oral, nasal and surgeries in prone position .
•MPC lll and lV patients
•Enlisted patients who needed more than one intubation attempt or developed any intra operative or post operative complication
•Known allergy to study drug.

结局指标

主要结局

To compare the effectiveness of preoperative nebulization of Dexamethasone for prevention of POST in patients undergoing general anaesthesia with endotracheal intubation.

时间窗: AFTER EXTUBATION,AFTER 2HOURS,AFTER 4HOURS,AFTER 6HOURS,AFTER 12HOURS AND AFTER 24HOURS.

次要结局

To compare the effectiveness of preoperative nebulization of Ketamine for prevention of POST in patients undergoing general anaesthesia with endotracheal intubation.(AFTER EXTUBATION,AFTER 2HOURS,AFTER 4HOURS,AFTER 6HOURS,AFTER 12HOURS AND AFTER 24HOURS.)

研究者

发起方

Dr KUDARY NEETHI PRIYANKA

申办方类型

Private medical college

研究点 (1)

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