COMPARISON BETWEEN NEBULIZATION WITH DEXAMETHASONE AND NEBULIZATION WITH KETAMINE TO PREVENT POST OPERATIVE SORE THROAT IN PATIENTS UNDERGOING ENDOTRACHEAL INTUBATION.

Not yet recruiting

• Conditions: ASA 1 AND ASA II

• Registration Number: CTRI/2023/08/057074
• Lead Sponsor: Dr KUDARY NEETHI PRIYANKA

Brief Summary

It is a randomized, prospective, comparative, double binded, observational study where preoperative  nebulization with dexamethasone and  preoperative nebulization with ketamine are compared to reduce post operative sore throat in patients undergoing general anaesthesia with endotracheal intubation.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2023-08-29
• Study Start: 2023-11-09

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

• 1.Patients aged between 18 to 60 years 2.
• American Society of Anaesthesiology (ASA) grade I and II 3.
• Hemodynamically stable patients with all routine investigations within the normal limits requiring GA with endotracheal intubation.

Exclusion Criteria

• Patient with a history of pre operative upper respiratory tract infection 2.
• History of asthma, recent use of non-steroidal anti inflammatory drugs 3.
• Undergoing head and neck surgeries, oral, nasal and surgeries in prone position .
• MPC lll and lV patients 5.
• Enlisted patients who needed more than one intubation attempt or developed any intra operative or post operative complication 6.
• Known allergy to study drug.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the effectiveness of preoperative nebulization of Dexamethasone for prevention of POST in patients undergoing general anaesthesia with endotracheal intubation.	AFTER EXTUBATION,AFTER 2HOURS,AFTER 4HOURS,AFTER 6HOURS,AFTER 12HOURS AND AFTER 24HOURS.

Secondary Outcome Measures

Name	Time	Method
To compare the effectiveness of preoperative nebulization of Ketamine for prevention of POST in patients undergoing general anaesthesia with endotracheal intubation.	AFTER EXTUBATION,AFTER 2HOURS,AFTER 4HOURS,AFTER 6HOURS,AFTER 12HOURS AND AFTER 24HOURS.

Trial Locations

Locations (1)

Dr.D.Y.PATIL MEDICAL COLLEGE HOSPITAL AND RESEARCH CENTRE SANT TUKARAM NAGAR PIMPRI PUNE; 🇮🇳 Pune, MAHARASHTRA, India

Dr.D.Y.PATIL MEDICAL COLLEGE HOSPITAL AND RESEARCH CENTRE SANT TUKARAM NAGAR PIMPRI PUNE

🇮🇳Pune, MAHARASHTRA, India

Dr KUDARY NEETHI PRIYANKA

Principal investigator

7601087425

neethipriyankakudary@gmail.com