The effect of ? syr in allergic rhinitis patients in the pilot study
Not Applicable
Recruiting
- Conditions
- allergic rhinitis.Allergic rhinitis due to pollenJ30.1
- Registration Number
- IRCT20081024001391N4
- Lead Sponsor
- Shahed University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Allergic rhinitis, both seasonal and permanent (intermittent and continuous)
Having criteria for allergic rhinitis based on the ARIA form
Exclusion Criteria
The presence of chronic diseases such as asthma, diabetes, cancer, as well as trauma and recent nose surgery, and women who are pregnant and breastfeeding.
Taking any chemical and herbal medicine known to be effective on allergic rhinitis
lack of literacy
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Gene expression levels of IL-5, IL-17A, interferon gamma, IL-4, IL-10, IL-13. Timepoint: The medicine will be taken for 4 weeks. Blood sampling will be at the beginning of the study and after the end of the medication in the fourth week. Method of measurement: with laboratory tests, respectively 1. Isolation of peripheral blood mononuclear cells (PBMCs); 2. Total RNA extraction; 3. cDNA synthesis; 4. Quantitative Real-Time PCR (qRT-PCR)Open in Google Translate•F.
- Secondary Outcome Measures
Name Time Method Drug side effects. Timepoint: Second and fourth week. Method of measurement: Medication side effects questionnaire.