Feasibility study of HD-DRUM - a novel drumming training app for people with Huntington's disease
- Conditions
- Improving cognitive and motor symptoms with drumming in people with Huntington's diseaseNervous System Diseases
- Registration Number
- ISRCTN11906973
- Lead Sponsor
- Cardiff University
- Brief Summary
2023 Other publications in https://pubmed.ncbi.nlm.nih.gov/37801351/ Intervention design (added 06/02/2024) 2024 Protocol article in https://pubmed.ncbi.nlm.nih.gov/39089721/ (added 02/08/2024)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Ongoing
- Sex
- All
- Target Recruitment
- 50
Current inclusion criteria as of 06/02/2024:
Individuals over the age of 18 years with premanifest or early/moderate manifest HD as confirmed by genetic testing for the presence of the mutant huntingtin allele with a Total Functional Capacity score between 9 and 13, sufficient motor control to perform drumming and on stable medication for a minimum of four weeks prior to enrolment.
Previous inclusion criteria:
Individuals over the age of 18 years with premanifest or early/moderate manifest HD as confirmed by genetic testing for the presence of the mutant huntingtin allele with sufficient motor control to perform drumming and on stable medication for a minimum of four weeks prior to enrolment. They will have participated in at least two cognitive testing sessions for the ENROLL-HD registry to reduce the burden (cognitive data collected within a month prior to pilot will be used as baseline data) and practice effects of repeated testing.
A history of any other neurological condition than HD and an inability to provide consent.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Feasibility of recruitment will be assessed by recording the number of participants enrolled and consented into the study per clinic per month.<br>2. Retention will be measured by the number of participants who complete the study. Number and study and non-study-related reasons for drop-out will be recorded.<br>3. Acceptability will be measured with a semi-quantitative self-report questionnaire asking participants to rate how engaging/motivating/frustrating the training was, whether the training frequency, duration, and difficulty was appropriate, whether they perceived any beneficial/detrimental training effects, what they liked/disliked and what aspects could be improved. This information will provide feedback for any adjustments that may need to be made to HD-DRUM in preparation for a future RCT.<br>4. Adherence to the training will be automatically tracked with HD-DRUM by recording the frequency and duration of training sessions.
- Secondary Outcome Measures
Name Time Method