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Clinical Trials/JPRN-UMIN000037430
JPRN-UMIN000037430
Completed
未知

Effect of Frailty on Elderly Patients Receiving Intensive Care: Prospective Multicenter Observational Study - LIFE (Looking into Intensive care setting on Frailty of Elderly) study

Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Department of Emergency, Critical Care, and Disaster Medicine0 sites650 target enrollmentJuly 21, 2019

Overview

Phase
未知
Intervention
Not specified
Conditions
Patients recieving intesive care. Patients aged over 65.
Sponsor
Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Department of Emergency, Critical Care, and Disaster Medicine
Enrollment
650
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

955 cases were screened for eligibility, 650 was included in the study. The median age was 79 (IQR 72-85) years. Overall mortality at 6-month was 21% ranging from CFS1: 6.2% to CFS>7: 42.9%. Six-month mortality increased with higher CFS. CFS was an independent prognostic factor (one-point increase in CFS, adjusted RR: 1.19 [1.09 - 1.30]). Quality of life (EQ5D index and VAS) worsened with higher CFS. Proportion of patients who could directly discharge home decreased with higher CFS.

Registry
who.int
Start Date
July 21, 2019
End Date
August 31, 2020
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Department of Emergency, Critical Care, and Disaster Medicine

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Patients with missing Clinical Frailty Scale before the transport.

Outcomes

Primary Outcomes

Not specified

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