A study to determine relation between alterations in senses of the tongue and tumour factors in oral tongue cancers
- Conditions
- Health Condition 1: C029- Malignant neoplasm of tongue, unspecified
- Registration Number
- CTRI/2021/06/034387
- Lead Sponsor
- o funding sources
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion criteria
1.Treatment naïve patients with squamous cell carcinoma of the oral tongue
2.T1-T4 staged disease
3.Patients who will undergo definitive surgical management
4.Age greater than or equal to 18 years
Exclusion criteria
1.Patients having any history of mental illness (depression, anxiety, etc) and currently taking medication for the same
2.Patients taking any form of week or strong opioid analgesics as per the WHO pain scale ladder, for a period greater than 1 week
3.Patients having a history of other diseases and conditions where taste sensation is disturbed such as Sjogrenâ??s syndrome, radiotherapy, etc.
4.Patients who have had COVID-19 previously
5.Patients who do not know how to read English, Hindi or Marathi
6.Patients with trismus and with ankyloglossia
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Endpoints <br/ ><br>Primary endpoint <br/ ><br>1.To determine the preoperative pain scores on the Brief Pain Index (BPI) that correlate with presence of perineural invasion/other adverse pathologic factors <br/ ><br>Timepoint: Pre surgery at baseline
- Secondary Outcome Measures
Name Time Method Secondary endpoint <br/ ><br>2.To determine if pre-operative dysguesia correlates with the presence perineural invasion/other adverse pathologic factors <br/ ><br>3.To determine if pre-operative focal sensations (light touch and two-point discrimination) correlates with the presence perineural invasion/ other adverse pathologic factors <br/ ><br>Timepoint: Pre surgery at baseline