NL-OMON56238招募中不适用
Plant stanol esters in the prevention of clinical symptoms related to asthma: the PLANTASTIC trial - Plant stanol esters and preventing asthma symptoms
Medisch Universitair Ziekenhuis Maastricht0 个研究点目标入组 300 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 300
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- Having allergic asthma (step 1-4 according to GINA 2019 guidelines), stable
- •at the moment of inclusion
- •- Have been treated with low or medium dose inhalation corticosteroids in
- •combination with a SABA or LABA, or as-needed low dose ICS-formoterol, or
- •appropriate alternative medication according to the GINA guidelines for at
- •least one year
- •- Aged 18-70
- •- BMI between 20 and 35 kg/m2
- •- Willing to abstain from products containing plant sterols and/or stanols one
- •month before and during the study
- •- Willing to keep the intake of fish oil supplements constant during the study
排除标准
- •- Currently smoking or quitted smoking in the past year, with a maximum of 10
- •packyears as smoking history (packyears = packs per day * years of smoking)
- •- Allergy to an ingredient of the soft chews
- •- Treatment with HMG-CoA reductase inhibitors (statins) to lower serum
- •cholesterol
- •- Suffering from inflammatory diseases (for CVD, illness must be minimally 3
- •years ago and currently under control in order to participate in the study)
- •- Fasting plasma glucose > 7.0 mmol/L
- •- Fasting serum TC > 8.0 mmol/L
- •- Having donated blood within one month prior to the start of the study, or
- •planning to donate blood during the study
- •- Pregnant women
- •- Breastfeeding women
研究者
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